A study conducted by researchers at the Spanish National Research Council (CSIC) has just identified a new therapeutic target for the treatment of Alzheimer’s disease.
A study conducted by researchers at the Spanish National Research Council (CSIC) has just identified a new therapeutic target for the treatment of Alzheimer’s disease. Alzheimer’s.
According to this study, SFRP1 (Secreted Frizzled Related Protein 1) levels are abnormally high and continue to increase with disease progression. In mice, it has been found that when the function of this protein is inactivated, disease progression is prevented.
The researchers argue that, because the disease has a multifactorial origin, the new approaches studied should be designed against factors that act simultaneously on more than one of the disease’s pathologically modified processes.
This latest study identifies that SFRP1 protein is one of the factors that act in multiple processes and that high levels of this protein are pathogenic. Just like that, innovations in the disease are based on the fact that the neutralization of the SFRP1 protein could be a very interesting therapeutic alternative. Although it requires further study, further research in this area should not be ruled out.
In return, they provide data on the future of Alzheimer’s disease because measuring SFRP1 levels in cerebrospinal fluid could also become a very useful diagnostic marker.
Facts about Alzheimer’s disease
The Spanish Society of Neurology (SEN) provides data on this disease and determines that some 800,000 people in Spain suffer from Alzheimer’s disease. Although they determine that with the increase in the prevalence of the disease over the years, the progressive aging of the population indicates that the number of cases will increase over the next few decades.
The disease is so important that this and other dementias are already localized, such as Alzheimer’s disease and related dementias. second specific cause of death in Spain. The SEN provides more data because each year, about 40,000 new cases of Alzheimer’s disease are diagnosed in Spain.
And every 66 seconds, someone in the United States of America develops the disease. According to the BrightFocus Foundation, approximately 500,000 new cases of this disease will be diagnosed this year.